Kate Moss has enjoyed playing guitar since her teens, but it wasn’t until she met Buddy Guy at the age of 21 that she realized what genre of music commanded her focus: The Blues. Exploring Buddy's music and that of his contemporaries, she fell in love with the sound and the heartfelt, improvisational nature of the Blues. Over the years, Kate has been honored to share the stage with not only Buddy on several occasions, but other top performers in the biz, like her husband Nick Moss, Jimmy Vivino, Tommy Castro, Jimmy Johnson, Walter Trout, Eddie Shaw, Curtis Salgado, Ana Popovic, Smokin’ Joe Kubek, Lurrie Bell, and Mud Morganfield, among many others.

In 2012 Kate was part of an all-star outfit, The Healers, which also included members Jimmy Hall (of Wet Willie), Reese Wynans (of SRV’s Double Trouble and now Joe Bonamassa's band), Samantha Fish, and Danielle and Kris Schnebelen (of Trampled Under Foot). The Healers released a critically-acclamed DVD/CD Live At Knuckleheads, with net proceeds from sales benefitting Blue Star Connection. Today Kate performs weekly with The Smiley Tillmon Band in and around Chicago, and hits the road from time to time for special events and festivals.